Specific Depletion of Ly6C(hi) Inflammatory Monocytes Prevents Immunopathology in Experimental Cerebral Malaria

Plasmodium berghei ANKA (PbA) infection of C57BL/6 mice leads to experimental cerebral malaria (ECM) that is commonly associated with serious T cell mediated damage. In other parasitic infection models, inflammatory monocytes have been shown to regulate Th1 responses but their role in ECM remains po...

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發表在:PLoS One
Main Authors: Schumak, Beatrix, Klocke, Katrin, Kuepper, Janina M., Biswas, Aindrila, Djie-Maletz, Andrea, Limmer, Andreas, van Rooijen, Nico, Mack, Matthias, Hoerauf, Achim, Dunay, Ildiko Rita
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401438/
https://ncbi.nlm.nih.gov/pubmed/25884830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124080
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