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CRAC channel inhibition produces greater anti-inflammatory effects than glucocorticoids in COPD CD8 cells
BACKGROUND: There are increased numbers of pulmonary CD8 lymphocytes in COPD. Calcium-release activation calcium (CRAC) channels play a central role in lymphocyte activation though the regulation of the transcription factor nuclear factor of activated T cells (NFAT). OBJECTIVE: We studied the expres...
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| Publicado no: | Clin Sci (Lond) |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4401013/ https://ncbi.nlm.nih.gov/pubmed/23905758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20130152 |
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