PKD1 Protein Is Involved in Reactive Oxygen Species-mediated Mitochondrial Depolarization in Cooperation with Protein Kinase Cδ (PKCδ)

In this study, we used gene targeting in mice to identify the in vivo functions of PKD1. In addition to phenotypically characterizing the resulting knock-out animals, we also used mouse embryonic fibroblasts to investigate the associated signaling pathways in detail. This study is the first to use g...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhang, Thianzhou, Sell, Philip, Braun, Ursula, Leitges, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400355/
https://ncbi.nlm.nih.gov/pubmed/25759386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619148
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