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PKD1 Protein Is Involved in Reactive Oxygen Species-mediated Mitochondrial Depolarization in Cooperation with Protein Kinase Cδ (PKCδ)

In this study, we used gene targeting in mice to identify the in vivo functions of PKD1. In addition to phenotypically characterizing the resulting knock-out animals, we also used mouse embryonic fibroblasts to investigate the associated signaling pathways in detail. This study is the first to use g...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Zhang, Thianzhou, Sell, Philip, Braun, Ursula, Leitges, Michael
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400355/
https://ncbi.nlm.nih.gov/pubmed/25759386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619148
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