Type I Interferon Controls Propagation of Long Interspersed Element-1

Type I interferons (IFN) including IFNα and IFNβ are critical for the cellular defense against viruses. Here we report that increased levels of IFNβ were found in testes from mice deficient in MOV10L1, a germ cell-specific RNA helicase that plays a key role in limiting the propagation of retrotransp...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yu, Qiujing, Carbone, Christopher J., Katlinskaya, Yuliya V., Zheng, Hui, Zheng, Ke, Luo, Mengcheng, Wang, P. Jeremy, Greenberg, Roger A., Fuchs, Serge Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400334/
https://ncbi.nlm.nih.gov/pubmed/25716322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612374
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