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Tyrosine Phosphorylation of GABA(A) Receptor γ2-Subunit Regulates Tonic and Phasic Inhibition in the Thalamus

GABA-mediated tonic and phasic inhibition of thalamic relay neurons of the dorsal lateral geniculate nucleus (dLGN) was studied after ablating tyrosine (Y) phosphorylation of receptor γ2-subunits. As phosphorylation of γ2 Y365 and Y367 reduces receptor internalization, to understand their importance...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Nani, Francesca, Bright, Damian P., Revilla-Sanchez, Raquel, Tretter, Verena, Moss, Stephen J., Smart, Trevor G.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400286/
https://ncbi.nlm.nih.gov/pubmed/23904608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0388-13.2013
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