Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro

STUDY QUESTION: Do endometrial stromal fibroblasts (eSF) in women with polycystic ovary syndrome (PCOS) (eSF(pcos)) exhibit altered estrogen and/or progesterone (P(4)) responses, which may explain some of the adverse reproductive outcomes and endometrial pathologies in these women? SUMMARY ANSWER: I...

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Detalhes bibliográficos
Publicado no:Hum Reprod
Main Authors: Piltonen, T.T., Chen, J.C., Khatun, M., Kangasniemi, M., Liakka, A., Spitzer, T., Tran, N., Huddleston, H., Irwin, J.C., Giudice, L.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400200/
https://ncbi.nlm.nih.gov/pubmed/25750105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dev055
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