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Intravital Imaging of a Massive Lymphocyte Response in the Cortical Dura of Mice after Peripheral Infection by Trypanosomes

Peripheral infection by Trypanosoma brucei, the protozoan responsible for sleeping sickness, activates lymphocytes, and, at later stages, causes meningoencephalitis. We have videoed the cortical meninges and superficial parenchyma of C56BL/6 reporter mice infected with T.b.brucei. By use of a two-ph...

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Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: Coles, Jonathan A., Myburgh, Elmarie, Ritchie, Ryan, Hamilton, Alana, Rodgers, Jean, Mottram, Jeremy C., Barrett, Michael P., Brewer, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400075/
https://ncbi.nlm.nih.gov/pubmed/25881126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003714
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