The Serotype Distribution among Healthy Carriers before Vaccination Is Essential for Predicting the Impact of Pneumococcal Conjugate Vaccine on Invasive Disease

Pneumococcal conjugate vaccines (PCVs) have substantially reduced morbidity and mortality of pneumococcal disease. The impact of the 7-valent PCV on all-serotype invasive pneumococcal disease (IPD) among children was reported to vary between high-income countries. We investigate the ability to predi...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Flasche, Stefan, Le Polain de Waroux, Olivier, O’Brien, Katherine L., Edmunds, W. John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400047/
https://ncbi.nlm.nih.gov/pubmed/25879748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004173
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