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Molecular Subtypes in Stage II-III Colon Cancer Defined by Genomic Instability: Early Recurrence-Risk Associated with a High Copy-Number Variation and Loss of RUNX3 and CDKN2A
OBJECTIVE: We sought to investigate various molecular subtypes defined by genomic instability that may be related to early death and recurrence in colon cancer. METHODS: We sought to investigate various molecular subtypes defined by instability at microsatellites (MSI), changes in methylation patter...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4399912/ https://ncbi.nlm.nih.gov/pubmed/25879218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122391 |
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