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The Epigenetic Regulator G9a Mediates Tolerance to RNA Virus Infection in Drosophila

Little is known about the tolerance mechanisms that reduce the negative effects of microbial infection on host fitness. Here, we demonstrate that the histone H3 lysine 9 methyltransferase G9a regulates tolerance to virus infection by shaping the response of the evolutionary conserved Jak-Stat pathwa...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Merkling, Sarah H., Bronkhorst, Alfred W., Kramer, Jamie M., Overheul, Gijs J., Schenck, Annette, Van Rij, Ronald P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399909/
https://ncbi.nlm.nih.gov/pubmed/25880195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004692
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