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The Epigenetic Regulator G9a Mediates Tolerance to RNA Virus Infection in Drosophila

Little is known about the tolerance mechanisms that reduce the negative effects of microbial infection on host fitness. Here, we demonstrate that the histone H3 lysine 9 methyltransferase G9a regulates tolerance to virus infection by shaping the response of the evolutionary conserved Jak-Stat pathwa...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Merkling, Sarah H., Bronkhorst, Alfred W., Kramer, Jamie M., Overheul, Gijs J., Schenck, Annette, Van Rij, Ronald P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399909/
https://ncbi.nlm.nih.gov/pubmed/25880195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004692
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