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The Epigenetic Regulator G9a Mediates Tolerance to RNA Virus Infection in Drosophila

Little is known about the tolerance mechanisms that reduce the negative effects of microbial infection on host fitness. Here, we demonstrate that the histone H3 lysine 9 methyltransferase G9a regulates tolerance to virus infection by shaping the response of the evolutionary conserved Jak-Stat pathwa...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Merkling, Sarah H., Bronkhorst, Alfred W., Kramer, Jamie M., Overheul, Gijs J., Schenck, Annette, Van Rij, Ronald P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399909/
https://ncbi.nlm.nih.gov/pubmed/25880195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004692
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