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Synthetic lethals in HIV: ways to avoid drug resistance: Running title: Preventing HIV resistance
BACKGROUND: RNA viruses rapidly accumulate genetic variation, which can give rise to synthetic lethal (SL) and deleterious (SD) mutations. Synthetic lethal mutations (non-lethal when alone but lethal when combined in one genome) have been studied to develop cancer therapies. This principle can also...
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| Publicat a: | Biol Direct |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4399722/ https://ncbi.nlm.nih.gov/pubmed/25888435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0044-y |
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