Mutation breeding of high 4-androstene-3,17-dione-producing Mycobacterium neoaurum ZADF-4 by atmospheric and room temperature plasma treatment

Steroid medication is used extensively in clinical applications and comprises a large and vital part of the pharmaceutical industry. However, the difficulty of separating 4-androstene-3,17-dione (AD) from 1,4-androstadiene-3,17-dione (ADD) restricts the application of the microbial transformation of...

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Vydáno v:J Zhejiang Univ Sci B
Hlavní autoři: Liu, Chao, Zhang, Xian, Rao, Zhi-Ming, Shao, Ming-Long, Zhang, Le-Le, Wu, Dan, Xu, Zheng-Hong, Li, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Zhejiang University Press 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399429/
https://ncbi.nlm.nih.gov/pubmed/25845362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1400274
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