HPV-16 impairs the subcellular distribution and levels of expression of protein phosphatase 1γ in cervical malignancy

BACKGROUND: The high risk Human Papillomavirus (HPV) E6 oncoproteins play an essential role in the development of cervical malignancy. Important cellular targets of E6 include p53 and the PDZ domain containing substrates such as hScrib and Dlg. We recently showed that hScrib activity was mediated in...

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Vydáno v:BMC Cancer
Hlavní autoři: Seiki, Takayuki, Nagasaka, Kazunori, Kranjec, Christian, Kawana, Kei, Maeda, Daichi, Nakamura, Hiroe, Taguchi, Ayumi, Matsumoto, Yoko, Arimoto, Takahide, Wada-Hiraike, Osamu, Oda, Katsutoshi, Nakagawa, Shunsuke, Yano, Tetsu, Fukayama, Masashi, Banks, Lawrence, Osuga, Yutaka, Fujii, Tomoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399203/
https://ncbi.nlm.nih.gov/pubmed/25886518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1141-0
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