HPV-16 impairs the subcellular distribution and levels of expression of protein phosphatase 1γ in cervical malignancy

BACKGROUND: The high risk Human Papillomavirus (HPV) E6 oncoproteins play an essential role in the development of cervical malignancy. Important cellular targets of E6 include p53 and the PDZ domain containing substrates such as hScrib and Dlg. We recently showed that hScrib activity was mediated in...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Cancer
Prif Awduron: Seiki, Takayuki, Nagasaka, Kazunori, Kranjec, Christian, Kawana, Kei, Maeda, Daichi, Nakamura, Hiroe, Taguchi, Ayumi, Matsumoto, Yoko, Arimoto, Takahide, Wada-Hiraike, Osamu, Oda, Katsutoshi, Nakagawa, Shunsuke, Yano, Tetsu, Fukayama, Masashi, Banks, Lawrence, Osuga, Yutaka, Fujii, Tomoyuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399203/
https://ncbi.nlm.nih.gov/pubmed/25886518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1141-0
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