Alga-Produced Malaria Transmission-Blocking Vaccine Candidate Pfs25 Formulated with a Human Use-Compatible Potent Adjuvant Induces High-Affinity Antibodies That Block Plasmodium falciparum Infection of Mosquitoes

A vaccine to prevent the transmission of malaria parasites from infected humans to mosquitoes is an important component for the elimination of malaria in the 21st century, yet it remains neglected as a priority of malaria vaccine development. The lead candidate for Plasmodium falciparum transmission...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Patra, Kailash P., Li, Fengwu, Carter, Darrick, Gregory, James A., Baga, Sheyenne, Reed, Steven G., Mayfield, Stephen P., Vinetz, Joseph M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399074/
https://ncbi.nlm.nih.gov/pubmed/25690099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02980-14
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