High-Throughput, Signature-Tagged Mutagenic Approach To Identify Novel Virulence Factors of Yersinia pestis CO92 in a Mouse Model of Infection

The identification of new virulence factors in Yersinia pestis and understanding their molecular mechanisms during an infection process are necessary in designing a better vaccine or to formulate an appropriate therapeutic intervention. By using a high-throughput, signature-tagged mutagenic approach...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Ponnusamy, Duraisamy, Fitts, Eric C., Sha, Jian, Erova, Tatiana E., Kozlova, Elena V., Kirtley, Michelle L., Tiner, Bethany L., Andersson, Jourdan A., Chopra, Ashok K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399035/
https://ncbi.nlm.nih.gov/pubmed/25754198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02913-14
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