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PPAR-γ agonist rosiglitazone reverses perinatal nicotine exposure-induced asthma in rat offspring

In a rat model, downregulation of homeostatic mesenchymal peroxisome proliferator-activated receptor-γ (PPAR-γ) signaling following perinatal nicotine exposure contributes to offspring asthma, which can be effectively prevented by concomitant administration of PPAR-γ agonist rosiglitazone (RGZ). How...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Lung Cell Mol Physiol
Asıl Yazarlar: Liu, Jie, Sakurai, Reiko, Rehan, Virender K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398871/
https://ncbi.nlm.nih.gov/pubmed/25659902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00234.2014
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