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Chronic and selective inhibition of basolateral membrane Na-K-ATPase uniquely regulates brush border membrane Na absorption in intestinal epithelial cells

Na-K-ATPase, an integral membrane protein in mammalian cells, is responsible for maintaining the favorable intracellular Na gradient necessary to promote Na-coupled solute cotransport processes [e.g., Na-glucose cotransport (SGLT1)]. Inhibition of brush border membrane (BBM) SGLT1 is, at least in pa...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Manoharan, Palanikumar, Gayam, Swapna, Arthur, Subha, Palaniappan, Balasubramanian, Singh, Soudamani, Dick, Gregory M., Sundaram, Uma
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398852/
https://ncbi.nlm.nih.gov/pubmed/25652450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00355.2014
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