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Loss of survival factors and activation of inflammatory cascades in brain sympathetic centers in type 1 diabetic mice

Neuroinflammation and neurodegeneration have been observed in the brain in type 1 diabetes (T1D). However, little is known about the mediators of these effects. In T1D mice with 12- and 35-wk duration of diabetes we examined two mechanisms of neurodegeneration, loss of the neuroprotective factors in...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Hu, Ping, Thinschmidt, Jeffrey S., Caballero, Sergio, Adamson, Samuel, Cole, Louise, Chan-Ling, Tailoi, Grant, Maria B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398829/
https://ncbi.nlm.nih.gov/pubmed/25714673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00504.2014
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