Impact of release characteristics of sinomenine hydrochloride dosage forms on its pharmacokinetics in beagle dogs

AIM: To investigate the effect of release behavior of sustained-release dosage forms of sinomenine hydrochloride (SM•HCl) on its pharmacokinetics in beagle dogs. METHODS: The in vitro release behavior of two SM•HCl dosage forms, including commercial 12-h sustained-release tablets and 24-h sustained-...

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Publicat a:World J Gastroenterol
Autors principals: Sun, Jin, Shi, Jie-Ming, Zhang, Tian-Hong, Gao, Kun, Mao, Jing-Jing, Li, Bing, Sun, Ying-Hua, He, Zhong-Gui
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Inc 2005
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398706/
https://ncbi.nlm.nih.gov/pubmed/16052686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i29.4547
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