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Transverse relaxation dispersion of the p7 membrane channel from Hepatitis C virus reveals conformational breathing

The p7 membrane protein encoded by Hepatitis C virus (HCV) assembles into a homo-hexamer that selectively conducts cations. An earlier solution NMR structure of the hexameric complex revealed a funnel-like architecture and suggests that a ring of conserved asparagines near the narrow end of the funn...

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Vydáno v:J Biomol NMR
Hlavní autoři: Dev, Jyoti, Brüschweiler, Sven, Bo, Ouyang, Chou, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398636/
https://ncbi.nlm.nih.gov/pubmed/25724842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-015-9912-0
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