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Cell- and Developmental Stage-Specific Dicer1 Ablation in the Lung Epithelium Models Cystic Pleuropulmonary Blastoma
Inherited syndromes provide unique opportunities to identify key regulatory mechanisms governing human disease. We previously identified germline loss-of-function DICER1 mutations in a human syndrome defined by the childhood lung neoplasm, pleuropulmonary blastoma (PPB), which arises during lung dev...
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| Publicado no: | J Pathol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398601/ https://ncbi.nlm.nih.gov/pubmed/25500911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4500 |
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