Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats

Androstenedione, the main circulating ovarian hormone present after menopause, has been shown to positively correlate with poor spatial memory in an ovary-intact rodent model of follicular depletion, and to impair spatial memory when administered exogenously to surgically menopausal ovariectomized r...

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Detalhes bibliográficos
Publicado no:Steroids
Main Authors: Mennenga, Sarah E., Koebele, Stephanie V., Mousa, Abeer A., Alderete, Tanya J., Tsang, Candy W.S., Acosta, Jazmin I., Camp, Bryan W., Demers, Laurence M., Bimonte-Nelson, Heather A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398574/
https://ncbi.nlm.nih.gov/pubmed/25159107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2014.08.010
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