Mitochondrial Modulation by Epigallocatechin 3-Gallate Ameliorates Cisplatin Induced Renal Injury through Decreasing Oxidative/Nitrative Stress, Inflammation and NF-kB in Mice

Cancer chemotherapy drug cisplatin is known for its nephrotoxicity. The aim of this study is to investigate whether Epigallocatechin 3-Gallate (EGCG) can reduce cisplatin mediated side effect in kidney and to understand its mechanism of protection against tissue injury. We used a well-established 3-...

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Bibliographic Details
Published in:PLoS One
Main Authors: Pan, Hao, Chen, Jun, Shen, Kezhen, Wang, Xueping, Wang, Ping, Fu, Guanghou, Meng, Hongzhou, Wang, Yimin, Jin, Baiye
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398485/
https://ncbi.nlm.nih.gov/pubmed/25875356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124775
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