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Identification and properties of plasma membrane azole efflux pumps from the pathogenic fungi Cryptococcus gattii and Cryptococcus neoformans

OBJECTIVES: Cryptococcus gattii from the North American Northwest (NW) have higher azole MICs than do non-NW C. gattii or Cryptococcus neoformans. Since mechanisms of azole resistance in C. gattii are not known, we identified C. gattii and C. neoformans plasma membrane azole efflux pumps and charact...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Basso, Luiz R., Gast, Charles E., Bruzual, Igor, Wong, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398472/
https://ncbi.nlm.nih.gov/pubmed/25630649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku554
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