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Smad1&5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis towards the postnatal state

Hair follicles (HFs) are regenerative mini-organs that offer a highly informative model system to study the regulatory mechanisms of hair follicle stem cells (hfSCs) homeostasis and differentiation. Bone Morphogenetic Protein (BMP) signaling is key in both of these processes, governing hfSCs quiesce...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Kandyba, Eve, Hazen, Virginia M., Kobielak, Agnieszka, Butler, Samantha J., Kobielak, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398393/
https://ncbi.nlm.nih.gov/pubmed/24023003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1548
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