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Smad1&5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis towards the postnatal state

Hair follicles (HFs) are regenerative mini-organs that offer a highly informative model system to study the regulatory mechanisms of hair follicle stem cells (hfSCs) homeostasis and differentiation. Bone Morphogenetic Protein (BMP) signaling is key in both of these processes, governing hfSCs quiesce...

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Publicat a:Stem Cells
Autors principals: Kandyba, Eve, Hazen, Virginia M., Kobielak, Agnieszka, Butler, Samantha J., Kobielak, Krzysztof
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398393/
https://ncbi.nlm.nih.gov/pubmed/24023003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1548
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