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Variational cross-validation of slow dynamical modes in molecular kinetics

Markov state models are a widely used method for approximating the eigenspectrum of the molecular dynamics propagator, yielding insight into the long-timescale statistical kinetics and slow dynamical modes of biomolecular systems. However, the lack of a unified theoretical framework for choosing bet...

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Bibliographic Details
Published in:J Chem Phys
Main Authors: McGibbon, Robert T., Pande, Vijay S.
Format: Artigo
Language:Inglês
Published: AIP Publishing LLC 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398134/
https://ncbi.nlm.nih.gov/pubmed/25833563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4916292
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