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Effect of Hyperketonemia (Acetoacetate) on Nuclear Factor-κB and p38 Mitogen-Activated Protein Kinase Activation Mediated Intercellular Adhesion Molecule 1 Upregulation in Endothelial Cells

Background: Hyperketonemia is a pathological condition observed in patients with type 1 diabetes and ketosis-prone diabetes (KPD), which results in increased blood levels of acetoacetate (AA) and β-hydroxybutyrate (BHB). Frequent episodes of hyperketonemia are associated with a higher incidence of v...

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Bibliografiske detaljer
Udgivet i:Metab Syndr Relat Disord
Main Authors: Rains, Justin L., Jain, Sushil K.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398000/
https://ncbi.nlm.nih.gov/pubmed/25489974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/met.2014.0101
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