Vancomycin-bearing Synthetic Bone Graft Delivers rhBMP-2 and Promotes Healing of Critical Rat Femoral Segmental Defects

BACKGROUND: Bone grafts simultaneously delivering therapeutic proteins and antibiotics may be valuable in orthopaedic trauma care. Previously, we developed a poly(2-hydroxyethyl methacrylate)-nanocrystalline hydroxyapatite (pHEMA-nHA) synthetic bone graft that, when preabsorbed with 400-ng rhBMP-2/7...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Orthop Relat Res
Main Authors: Skelly, Jordan D., Lange, Jeffrey, Filion, Tera M., Li, Xinning, Ayers, David C., Song, Jie
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2014
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397773/
https://ncbi.nlm.nih.gov/pubmed/25099263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-014-3841-1
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