Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

BACKGROUND: The endothelial glycocalyx layer (EGL) is a key regulator of vascular permeability, cell adhesion, and inflammation. The EGL is primarily composed of syndecan-1, hyaluronic acid (HA), heparan sulfate (HS) and chondroitin sulfate (CS). While many studies have observed increased shedding o...

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Dades bibliogràfiques
Publicat a:J Transl Med
Autors principals: Rahbar, Elaheh, Cardenas, Jessica C, Baimukanova, Gyulnar, Usadi, Benjamin, Bruhn, Roberta, Pati, Shibani, Ostrowski, Sisse R, Johansson, Pär I, Holcomb, John B, Wade, Charles E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397670/
https://ncbi.nlm.nih.gov/pubmed/25889764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0481-5
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