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Loss of Feedback Inhibition via D2 Autoreceptors Enhances Acquisition of Cocaine Taking and Reactivity to Drug-Paired Cues

A prominent aspect of drug addiction is the ability of drug-associated cues to elicit craving and facilitate relapse. Understanding the factors that regulate cue reactivity will be vital for improving treatment of addictive disorders. Low availability of dopamine (DA) D2 receptors (D2Rs) in the stri...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Holroyd, Kathryn B, Adrover, Martin F, Fuino, Robert L, Bock, Roland, Kaplan, Alanna R, Gremel, Christina M, Rubinstein, Marcelo, Alvarez, Veronica A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397408/
https://ncbi.nlm.nih.gov/pubmed/25547712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.336
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