Adult AMPA GLUA1 Receptor Subunit Loss in 5-HT Neurons Results in a Specific Anxiety-Phenotype with Evidence for Dysregulation of 5-HT Neuronal Activity

Both the glutamatergic and serotonergic (5-HT) systems are implicated in the modulation of mood and anxiety. Descending cortical glutamatergic neurons regulate 5-HT neuronal activity in the midbrain raphe nuclei through α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and N-methyl-D-aspar...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Weber, Tillmann, Vogt, Miriam A, Gartside, Sarah E, Berger, Stefan M, Lujan, Rafael, Lau, Thorsten, Herrmann, Elke, Sprengel, Rolf, Bartsch, Dusan, Gass, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397405/
https://ncbi.nlm.nih.gov/pubmed/25547714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.332
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