CDKN2A Loss Is Associated with Shortened Overall Survival in Lower Grade (World Health Organization II-III) Astrocytomas

Lower grade (WHO II-III) gliomas vary widely in clinical behavior and are classified as astrocytic, oligodendroglial, or mixed forms. Anaplasia depends greatly on mitotic activity, with CDKN2A loss considered the most common mechanism for cell cycle dysregulation. We investigated whether loss of the...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Reis, Gerald F., Pekmezci, Melike, Hansen, Helen M., Rice, Terri, Marshall, Roxanne E., Molinaro, Annette M., Phillips, Joanna J., Vogel, Hannes, Wiencke, John K., Wrensch, Margaret R., Walsh, Kyle M., Perry, Arie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397174/
https://ncbi.nlm.nih.gov/pubmed/25853694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0000000000000188
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