Social defeat promotes a reactive endothelium in a brain region-dependent manner with increased expression of key adhesion molecules, selectins and chemokines associated with the recruitment of myeloid cells to the brain

Repeated social defeat (RSD) in mice causes myeloid cell trafficking to the brain that contributes to the development of prolonged anxiety-like behavior. Myeloid cell recruitment following RSD occurs in regions where neuronal and microglia activation is observed. Thus, we hypothesized that crosstalk...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Sawicki, Caroline M., McKim, Daniel B., Wohleb, Eric S., Jarrett, Brant L., Reader, Brenda F., Norden, Diana M., Godbout, Jonathan P., Sheridan, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397120/
https://ncbi.nlm.nih.gov/pubmed/25445193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.10.004
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