Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction

Chronic obstructive lung disease determines morbidity and mortality of patients with cystic fibrosis (CF). CF airways are characterized by a nonresolving neutrophilic inflammation. After pathogen contact or prolonged activation, neutrophils release DNA fibres decorated with antimicrobial proteins, f...

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Bibliographic Details
Published in:Mediators Inflamm
Main Authors: Marcos, Veronica, Zhou-Suckow, Zhe, Önder Yildirim, Ali, Bohla, Alexander, Hector, Andreas, Vitkov, Ljubomir, Krautgartner, Wolf Dietrich, Stoiber, Walter, Griese, Matthias, Eickelberg, Oliver, Mall, Marcus A., Hartl, Dominik
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397025/
https://ncbi.nlm.nih.gov/pubmed/25918476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/408935
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