Renal Oxidative Stress Induced by Long-Term Hyperuricemia Alters Mitochondrial Function and Maintains Systemic Hypertension

We addressed if oxidative stress in the renal cortex plays a role in the induction of hypertension and mitochondrial alterations in hyperuricemia. A second objective was to evaluate whether the long-term treatment with the antioxidant Tempol prevents renal oxidative stress, mitochondrial alterations...

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Bibliografiske detaljer
Udgivet i:Oxid Med Cell Longev
Main Authors: Cristóbal-García, Magdalena, García-Arroyo, Fernando E., Tapia, Edilia, Osorio, Horacio, Arellano-Buendía, Abraham S., Madero, Magdalena, Rodríguez-Iturbe, Bernardo, Pedraza-Chaverrí, José, Correa, Francisco, Zazueta, Cecilia, Johnson, Richard J., Sánchez Lozada, Laura-Gabriela
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396880/
https://ncbi.nlm.nih.gov/pubmed/25918583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/535686
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