Iron chelation and redox chemistry of anthranilic acid and 3-hydroxyanthranilic acid: A comparison of two structurally related kynurenine pathway metabolites to obtain improved insights into their potential role in neurological disease development

Anthranilic acid (ANA) and 3-hydroxyanthranilic acid (3-HANA) are kynurenine pathway intermediates of the tryptophan metabolism. A hitherto unemployed method combination, differential pulse voltammetry, mass spectrometry (nano-ESI–MS), deoxyribose degradation and iron(II) autoxidation assays has bee...

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Veröffentlicht in:J Organomet Chem
Hauptverfasser: Chobot, Vladimir, Hadacek, Franz, Weckwerth, Wolfram, Kubicova, Lenka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Sequoia 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396858/
https://ncbi.nlm.nih.gov/pubmed/25892823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jorganchem.2015.01.005
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