Dipeptidyl Peptidase-4 Inhibitor Decreases Abdominal Aortic Aneurysm Formation through GLP-1-Dependent Monocytic Activity in Mice

Abdominal aortic aneurysm (AAA) is a life-threatening situation affecting almost 10% of elders. There has been no effective medication for AAA other than surgical intervention. Dipeptidyl peptidase-4 (DPP-4) inhibitors have been shown to have a protective effect on cardiovascular disease. Whether DP...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lu, Hsin Ying, Huang, Chun Yao, Shih, Chun Ming, Chang, Wei Hung, Tsai, Chein Sung, Lin, Feng Yen, Shih, Chun Che
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396852/
https://ncbi.nlm.nih.gov/pubmed/25876091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121077
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