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O-Glycosylation in Cell Wall Proteins in Scedosporium prolificans Is Critical for Phagocytosis and Inflammatory Cytokines Production by Macrophages

In this study, we analyze the importance of O-linked oligosaccharides present in peptidorhamnomannan (PRM) from the cell wall of the fungus Scedosporium prolificans for recognition and phagocytosis of conidia by macrophages. Adding PRM led to a dose-dependent inhibition of conidia phagocytosis, wher...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xisto, Mariana I. D. S., Bittencourt, Vera C. B., Liporagi-Lopes, Livia Cristina, Haido, Rosa M. T., Mendonça, Morena S. A., Sassaki, Guilherme, Figueiredo, Rodrigo T., Romanos, Maria Teresa V., Barreto-Bergter, Eliana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396840/
https://ncbi.nlm.nih.gov/pubmed/25875427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123189
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