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Novel Role of ROS-Activated trp Melastatin Channel-2 (TRPM2) in Mediating Angiogenesis and Post-Ischemic Neovascularisation
OBJECTIVE: Transient Receptor Potential Melastatin-2 (TRPM2) channel is a non-selective cation channel that mediates influx of Ca(2+) and Na(+) with relative permeability of PCa:PNa ∼0.6 in response to cellular oxidative stress. As angiogenesis and ischemic neovascularization are both significantly...
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Publicat a: | Arterioscler Thromb Vasc Biol |
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Autors principals: | , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4396825/ https://ncbi.nlm.nih.gov/pubmed/25675998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304802 |
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