Lipid starvation and hypoxia synergistically activate ICAM1 and multiple genes in an Sp1-dependent manner to promote the growth of ovarian cancer

BACKGROUND: Elucidation of the molecular mechanisms by which cancer cells overcome hypoxia is potentially important for targeted therapy. Complexation of hypoxia-inducible factors (HIFs) with aryl hydrocarbon receptor nuclear translocators can enhance gene expression and initiate cellular responses...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer
Autori principali: Koizume, Shiro, Ito, Shin, Nakamura, Yoshiyasu, Yoshihara, Mitsuyo, Furuya, Mitsuko, Yamada, Roppei, Miyagi, Etsuko, Hirahara, Fumiki, Takano, Yasuo, Miyagi, Yohei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396815/
https://ncbi.nlm.nih.gov/pubmed/25879517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0351-z
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