Methylation of Promoter Regions of Genes of the Human Intrauterine Renin Angiotensin System and Their Expression

The intrauterine renin angiotensin system (RAS) is implicated in placentation and labour onset. Here we investigate whether promoter methylation of RAS genes changes with gestation or labour and if it affects gene expression. Early gestation amnion and placenta were studied, as were term amnion, dec...

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Publicat a:Int J Endocrinol
Autors principals: Sykes, Shane D., Mitchell, Carolyn, Pringle, Kirsty G., Wang, Yu, Zakar, Tamas, Lumbers, Eugenie R.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396557/
https://ncbi.nlm.nih.gov/pubmed/25918528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/459818
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