Methylation of Promoter Regions of Genes of the Human Intrauterine Renin Angiotensin System and Their Expression

The intrauterine renin angiotensin system (RAS) is implicated in placentation and labour onset. Here we investigate whether promoter methylation of RAS genes changes with gestation or labour and if it affects gene expression. Early gestation amnion and placenta were studied, as were term amnion, dec...

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Udgivet i:Int J Endocrinol
Main Authors: Sykes, Shane D., Mitchell, Carolyn, Pringle, Kirsty G., Wang, Yu, Zakar, Tamas, Lumbers, Eugenie R.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396557/
https://ncbi.nlm.nih.gov/pubmed/25918528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/459818
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