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Rosiglitazone attenuates the metalloprotease/anti-metalloprotease imbalance in emphysema induced by cigarette smoke: involvement of extracellular signal-regulated kinase and NFκB signaling
OBJECTIVE: We investigated how rosiglitazone attenuated cigarette smoke (CS)-induced emphysema in a rat model. In particular, we focused on its possible effects on the imbalance between metalloprotease (MMP) and anti-MMP activity, mitogen-activated protein kinase (MAPK) phosphorylation, and nuclear...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Int J Chron Obstruct Pulmon Dis |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Dove Medical Press
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4396520/ https://ncbi.nlm.nih.gov/pubmed/25897215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S77514 |
| Tagiau: |
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