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MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation
Bone marrow mesenchymal stem cells (BMSCs) exhibit an age-dependent reduction in osteogenesis that is accompanied by an increased propensity toward adipocyte differentiation. This switch increases adipocyte numbers and decreases the number of osteoblasts, contributing to age-related bone loss. Here,...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4396470/ https://ncbi.nlm.nih.gov/pubmed/25751060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77716 |
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