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MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation

Bone marrow mesenchymal stem cells (BMSCs) exhibit an age-dependent reduction in osteogenesis that is accompanied by an increased propensity toward adipocyte differentiation. This switch increases adipocyte numbers and decreases the number of osteoblasts, contributing to age-related bone loss. Here,...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Li, Chang-Jun, Cheng, Peng, Liang, Meng-Ke, Chen, Yu-Si, Lu, Qiong, Wang, Jin-Yu, Xia, Zhu-Ying, Zhou, Hou-De, Cao, Xu, Xie, Hui, Liao, Er-Yuan, Luo, Xiang-Hang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396470/
https://ncbi.nlm.nih.gov/pubmed/25751060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77716
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