Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate

The inhibitor of the nuclear factor-κB (IκB) kinase (IKK) complex is a key regulator of the canonical NF-κB signalling cascade and is crucial for fundamental cellular functions, including stress and immune responses. The majority of IKK complex functions are attributed to NF-κB activation; however,...

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Publicado en:Nat Commun
Main Authors: Krishnan, Ramesh K., Nolte, Hendrik, Sun, Tianliang, Kaur, Harmandeep, Sreenivasan, Krishnamoorthy, Looso, Mario, Offermanns, Stefan, Krüger, Marcus, Swiercz, Jakub M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Pub. Group 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396366/
https://ncbi.nlm.nih.gov/pubmed/25849741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7658
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