Nephroblastoma overexpressed gene (NOV) enhances RCC cell motility through upregulation of ICAM-1 and COX-2 expression via Akt pathway

Renal cell carcinoma (RCC) carries a high risk of malignancy and metastasis. The inducible isoform of prostaglandin synthase, cyclooxygenase (COX)-2, and ICAM-1 may be involved in tumor metastasis. CCN3, also called nephroblastoma overexpressed gene (NOV), has been found to regulate the proliferatio...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Liu, Shuai, Han, Liping, Wang, Xiaoqing, Liu, Zheng, Ding, Sentai, Lu, Jiaju, Bi, Dongbin, Mei, Yikun, Niu, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396272/
https://ncbi.nlm.nih.gov/pubmed/25973014
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