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Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications

BACKGROUND: The Hygiene Hypothesis (HH) attributes the dramatic increase in autoimmune and allergic diseases observed in recent decades in Western countries to the reduced exposure to diverse immunoregulatory infectious agents. This theory has since largely been supported by strong epidemiological a...

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Dettagli Bibliografici
Pubblicato in:BMC Med
Autori principali: Versini, Mathilde, Jeandel, Pierre-Yves, Bashi, Tomer, Bizzaro, Giorgia, Blank, Miri, Shoenfeld, Yehuda
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396177/
https://ncbi.nlm.nih.gov/pubmed/25879741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-015-0306-7
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