Chromosomal rearrangement involving 11q23 locus in chronic myelogenous leukemia: a rare phenomenon frequently associated with disease progression and poor prognosis

BACKGROUND: Progression of chronic myelogenous leukemia (CML) is frequently accompanied by cytogenetic evolution, commonly unbalanced chromosomal changes, such as an extra copy of Philadelphia chromosome (Ph), +8, and i(17)(q10). Balanced chromosomal translocations typically found in de novo acute m...

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Veröffentlicht in:J Hematol Oncol
Hauptverfasser: Wang, Wei, Tang, Guilin, Cortes, Jorge E, Liu, Hui, Ai, Di, Yin, C Cameron, Li, Shaoying, Khoury, Joseph D, Bueso-Ramos, Carlos, Medeiros, L Jeffrey, Hu, Shimin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396174/
https://ncbi.nlm.nih.gov/pubmed/25888368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0128-2
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