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Downregulation of ER-α36 expression sensitizes HER2 overexpressing breast cancer cells to tamoxifen

Tamoxifen provided a successful treatment for ER-positive breast cancer for many years. However, HER2 overexpressing breast cancer cells respond poorly to tamoxifen therapy presumably by pass. The molecular mechanisms underlying development of tamoxifen resistance have not been well established. Rec...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Yin, Li, Pan, Xiaohua, Zhang, Xin-Tian, Guo, Yu-Ming, Wang, Zhao-Yi, Gong, Yaoqin, Wang, Molin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396031/
https://ncbi.nlm.nih.gov/pubmed/25973295
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