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Neurovirulent strains of Alphavirus induce apoptosis in bcl-2-expressing cells: role of a single amino acid change in the E2 glycoprotein.

The isolation and sequence comparison of avirulent and neurovirulent strains of polio virus, alpha virus, herpes virus, immunodeficiency virus, and other viruses have identified genetic changes that are required to cause disease in the nervous system. The molecular mechanisms by which these genetic...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ubol, S, Tucker, P C, Griffin, D E, Hardwick, J M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8197207/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.5202
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