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All-trans retinoid acid promotes allogeneic corneal graft survival in mice by regulating Treg-Th17 balance in the presence of TGF-β

BACKGROUND: All-trans retinoid acid (ATRA) has been proven to skew Regulatory T cell-T helper 17 cell (Treg-Th17) balance toward Treg in vitro, favoring graft acceptance. However, its in vivo effect after solid organ transplantation is under investigation. RESULTS: BALB/c mice were given orthotopic...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Immunol
Hauptverfasser: Wang, Xin, Wang, Wentao, Xu, Jianjiang, Wu, Suqian, Le, Qihua
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395899/
https://ncbi.nlm.nih.gov/pubmed/25887926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-015-0082-3
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